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More EAS - Electron Donating and Withdrawing Groups S01 E38

In the previous episode we discussed what happens when we use electrophilic aromatic substitution to add a group to a benzene ring, but what happens when you try to add even more groups? Well, things get a little more complicated. In this episode of Crash Course Organic Chemistry, we’ll continue our exploration of EAS reactions by looking at electron donating groups and electron withdrawing groups on benzene, and how they affect what happens when we try to add new groups to the ring.


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1
What Is Organic Chemistry?
2
The Basics of Organic Nomenclature
3
More Organic Nomenclature: Heteroatom Functional Groups
4
3D Structure and Bonding
5
IR Spectroscopy and Mass Spectrometry
6
Alkanes
7
Cyclohexanes
8
Stereochemistry
9
More Stereochemical Relationships
10
Polarity, Resonance, and Electron Pushing
11
Acidity
12
Nucleophiles and Electrophiles
13
Intro to Reaction Mechanisms
14
E/Z Alkenes, Electrophilic Addition, & Carbocations
15
Thermodynamics and Energy Diagrams
16
Alkene Addition Reactions
17
Alkene Redox Reactions
18
Alkyne Reactions & Tautomerization
19
Radical Reactions & Hammond's Postulate
20
Intro to Substitution Reactions
21
Substitution Reactions - SN1 and SN2 Mechanisms
22
E1 and E2 Reactions
23
Determining SN1, SN2, E1, and E2 Reactions
24
Alcohols, Ethers, and Epoxides
25
Synthesis and Column Chromatography
26
How to Identify Molecules - Proton NMR
27
An Overview of Aldehydes and Ketones
28
Organometallic Reagents and Carbanions
29
Aldehyde and Ketone Reactions - Hydrates, Acetals, & Imines
30
Carboxylic Acids
31
Carboxylic Acid Derivatives & Hydrolysis Reactions
32
Interconversion and Organometallics
33
Chemoselectivity and Protecting Groups
34
Retrosynthesis and Liquid-Liquid Extraction
35
Polymer Chemistry
36
Aromaticity, Hückel's Rule, and Chemical Equivalence in NMR
37
Intro to Electrophilic Aromatic Substitution
38
More EAS - Electron Donating and Withdrawing Groups
39
More EAS & Benzylic Reactions
40
Synthesis, Distillation, & Recrystallization
41
Conjugation & UV-Vis Spectroscopy
42
The Diels-Alder & Other Pericyclic Reactions
43
Enols and Enolates - Reactivity, Halogenation, and Alkylation
44
The Aldol and Claisen Reactions
45
Crossed Aldol Reactions, Enones, and Conjugate Addition
46
Amines
47
Diazonium Salts & Nucleophilic Aromatic Substitution
48
Biochemical Building Blocks & Fischer and Haworth Projections
49
Biological Polymers
50
Medicinal Chemistry and Penicillin Total Synthesis
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