Beth Bradfield (Patty Duke) is a housewife with what appears to be a stable life in an American village. One day, her 24-year-old daughter Lori (Tracey Gold), who is married to Jesse Molina (Maurice Benard) and recently gave birth to his daughter Molly (Laura and Megan Jaime), unexpectedly collapses and is hospitalized. After several tests, she is diagnosed with leukemia. Her doctor (Erick Avari) reveals to Beth that Lori is in urgent need of a donor, though her rare blood type makes finding one a difficult task.
Elizabeth Bentley is a successful lawyer who suddenly has some "punkish" daydreams of being "Rambo" right around the time her clueless boyfriend Brad asks her to marry him. After a therapy session, she quits her job to the surprise of her family and Brad, and goes into the detective business, opening her own private-eye office. Unfortunately, the ghost of the private-eye who owned the office still lingers and Elizabeth's the only one who can see or hear him. At first, she becomes an unwilling partner in Nick Peyton's unfinished investigation, but then she finds herself falling for the salty, but dead, guy.
Since the death of her husband 10 years ago, Evelyn has been working hard for her company, but had no private life. Now her doctor shocks her with the news that she may live only another 6 months. Spontanely she follows a TV ad and sets out for vacation in Mexico. There she meets widower Lloyd and they fall in love, go bungee jumping... until she gets another diagnosis from her doctor.
The Final Days concerns itself with the final months of the Richard Nixon presidency.
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